At SMi’s 2019 Pre-Crammed Syringes East Coast USA Convention, trade leaders will meet in Boston to share their insights on finest design observe, drug compatibility inside the entire provider chain and challenges with manufacturing and drug supply. Key highlights embrace:Cyclo Olefin Polymer (COP) – technical information replace• Key properties of COP• Case research. Biologics formulation for COP syringe optimized to eliminating use of surfactant• Case research. Examine on protein adsorption/aggregation – COP vs glass• Case research. Examine on delamination with glass syringe vs COP syringe• Leachable information on COP syringes with varied chemicalsKEYNOTE ADDRESSControl technique and design switch for pharmaceutical supply machine mixture merchandise• Set up management technique (CS) for PFS manufacturing together with machine constituent elements• Develop CS for supply machine throughout design transfers to establish important high quality attributes (CQAs) for machine constituent elements• Generate a set of controls, e.g. incoming, in-process, launch and/or stability specs for supply machine manufacturing• Promote communication between machine and drug improvement teams, improvement and manufacturing teams, pharma firm and machine part suppliers• Acknowledge the distinction between supply machine and drug: drug targeted extra on course of parameter (e.g. CPP) and machine targeted extra on materials attributes (e.g. CMA)The most effective plastic syringe for biologics• Multilayer plastic vial & syringe• Glorious oxygen and UV barrier contribute to stability of medicine• Very low extractables contribute to stability of medicine• Minimized silicone-oil contributes to stopping protein aggregationPFS / autoinjector compatibility – impacts to manufacturing and drug supply efficiency• What’s the PFS/Autoinjector compatibility?• Challenges to manufacturing and drug supply efficiency• Proposed solutionsSpeakers embrace:Toshiro Katayama, Product Supervisor, ZeonLing Lu, Sr. Principal Scientist, PfizerShota Arakawa, Enterprise Growth Researcher, Mitsubishi Gasoline Chemical CompanyJoyce Y Zhao, System Lead, Mixture Product Growth, TakedaMore particulars can be found on the web site http://www.pfsamericas.com/pr5Sponsored by:3P Innovation | Aptar Pharma | CSS (CONNECTICUT SPRING & STAMPING) | Harro Höfliger | LONSTROFF | MITSUBISHI GAS CHEMICAL | Owen Mumford | Polyplastics | RheoSense| SCHOTT | Steri-Tek | SUMITOMO RUBBER INDUSTRIES | West Pharmaceutical Companies | ZEON Contacts:Sponsorship, exhibition and branding packages: Alia Malick +44 (0)20 7827 6168 / [email protected] enquiries: Kieran Ronaldson on +44 (0) 20 7827 6744 / [email protected] enquiries contact Neill Howard +44 (0) 207 827 6164 [email protected] SMi Group:Established since 1993, the SMi Group is a worldwide event-production firm that makes a speciality of Enterprise-to-Enterprise Conferences, Workshops, Masterclasses and on-line Communities. We create and ship occasions within the Defence, Safety, Vitality, Utilities, Finance and Pharmaceutical industries. We satisfaction ourselves on getting access to the world’s most forward-thinking opinion leaders and visionaries, permitting us to convey our communities collectively to Study, Have interaction, Share and Community. Extra data may be discovered at http://www.smi-online.co.uk